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▄ ▄████▓▓▄▄▄ ▄ ▄ [ MOST PROUDLY PRESENTS ] ▄ ▄ ▄▄▄▓▓████▄ ▄
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SYBYL-X 2.0.0.11273
(c) Tripos
Date ..... : 2011-10-09
Size ..... : 14 x 50.00MB
Protection : FlexLM
Type ..... : Molecular Modeling
OS ....... : Windows
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─ ─────────────────────────────────────────────────────────────────────────── ─
░▓█████████████████████▓░ [ RELEASE NOTES ] ░▓██████████████████████▓░
─ ─────────────────────────────────────────────────────────────────────────── ─
SYBYL-X provides intuitive molecular modeling for life scientists
interested in drug and molecular design. Small molecule and macromolecular
modeling and simulation, cheminformatics, lead identification, lead
optimization techniques and more are possible with SYBYL-X.
Molecular Modeling from Sequence through Lead Optimization SYBYL-X.
Whether you need to find new lead candidates, optimize lead series, or
perform other related life science experiments like modeling a protein
structure, SYBYL-X has solutions to move your discovery research
forward. With capabilities for small molecule modeling and simulation,
macromolecular modeling and simulation, cheminformatics, lead
identification, and lead optimization, all wrapped up in an easy to use,
cost-effective interface, SYBYL-X has the tools and capabilities you
need for molecular design.
Additionally, the science offered by SYBYL-X provides unique, competitive
advantages in a number of areas vital for today's successful discovery
research:
* 3D QSAR: use the power of industry leading CoMFA in a new way to
generate novel ideas for R-groups - predict the level of biological
activity or potency based on structure-activity data, not just yes/no
activity predictions
* Ligand-based virtual screening: search millions of compounds overnight -
don't miss hits because you only screened subsetted portions of your database
* Cheminformatics: produce highly focused queries that avoid false
positives using rich set of 3D queries; on-the-fly conformational
searching means you only store a single conformation of your molecules,
keeping database size small and very transportable.
* Docking: custom tailor and fine-tune docking to a particular receptor
site using information like SAR or known poses to improve rank ordering
of ligands.
http://tripos.com/index.php?family=modules,SimplePage,,,&page=SYBYL-X
─ ─────────────────────────────────────────────────────────────────────────── ─
░▓█████████████████████▓░ [ INSTALLATION ] ░▓██████████████████████▓░
─ ─────────────────────────────────────────────────────────────────────────── ─
Unzip, Unrar, Install. Check /crack.
─ ─────────────────────────────────────────────────────────────────────────── ─
░▓█████████████████████▓░ [ GROUP iNFO ] ░▓██████████████████████▓░
─ ─────────────────────────────────────────────────────────────────────────── ─
We are not taking any applications. We are an invite only group.
─ ─────────────────────────────────────────────────────────────────────────── ─
░▓█████████████████████▓░ [ GREETINGS ] ░▓██████████████████████▓░
─ ─────────────────────────────────────────────────────────────────────────── ─
Our friends, our loyal members and our fair competitors.
You know who you are.
─ ─────────────────────────────────────────────────────────────────────────── ─
░▓████████████▓░ [ RECOiL IN 2011 - ONE MORE IMPACT! ] ░▓████████████▓░
─ ─────────────────────────────────────────────────────────────────────────── ─